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About

Vision

The Center for Mitochondrial Medicine (CMM) envisions a future where it stands at the forefront of medical research and clinical practice, setting new standards of excellence and innovation. The CMM is dedicated to being a hub of scholarly training, providing cutting-edge education and training programs that empower researchers and clinicians to advance the field of mitochondrial medicine.

The CMM is committed to establishing UT Health San Antonio as a globally recognized Center of Excellence in mitochondrial medicine, garnering recognition for its groundbreaking research, clinical care, and translational advancements. By fostering a culture of excellence, the CMM aims to be a beacon of inspiration and validation for the entire UT Health San Antonio community and beyond.

Mission

The CMM mission is to develop and implement cutting-edge chemical and biological tools that enable the identification and characterization of ion channels and receptors (parts), intracellular signaling modulators (pathways), and their roles in physiological function and disease progression (pathogenesis).

Key Elements of Our Mission:

  • Innovation: We strive to be at the forefront of scientific innovation by developing novel chemical and biological tools that push the boundaries of current knowledge. Our team of experts will continuously explore new technologies, techniques, and approaches to develop innovative solutions for studying ion channels, receptors, intracellular signaling modulators, and their functions in health and disease.
  • Interdisciplinary Approach: We recognize that understanding the complex interplay between ion channels, receptors, intracellular signaling modulators, and their roles in physiology and disease requires a multidisciplinary approach. Our team will collaborate across disciplines, including chemistry, biology, pharmacology, and medicine, to develop integrated tools that bridge the gap between different fields and provide a holistic understanding of these complex systems.
  • Rigorous Research: We are committed to conducting rigorous and reproducible research to ensure the reliability and validity of our tools. Our team will follow established scientific principles and standards in experimental design, data collection, analysis, and interpretation to generate high-quality data that can be used to advance our understanding of ion channels, receptors, intracellular signaling modulators, and their roles in physiological function and disease progression.
  • Translation to Application: Our mission is not only to generate knowledge but also to translate our findings into practical applications that can benefit society. We will work towards developing tools that can be readily applied in basic research, drug discovery, and clinical settings to advance the understanding of ion channels, receptors, intracellular signaling modulators, and their roles in health and disease. 
  • Collaboration and Partnerships: We recognize the value of collaboration and partnerships in advancing scientific research. We will actively seek collaborations with academic and industry partners to leverage their expertise and resources to accelerate the development and implementation of our chemical and biological tools. By fostering a collaborative environment, we aim to create synergistic collaborations that lead to breakthrough discoveries and meaningful impact.
  • Education and Outreach: We are committed to promoting scientific literacy and engaging with the broader community to raise awareness of the importance of ion channels, receptors, intracellular signaling modulators, and their roles in health and disease. We will actively engage in educational and outreach activities, such as workshops, seminars, and public lectures, to share our knowledge, inspire the next generation of scientists, and promote the translation of our research findings into practical applications for the benefit of society.

Research

Core Research Areas
  • Ion Channels
  • Mitochondrial Metabolism
  • Signal Transduction
  • Translational Medicine

Research Objectives

Leadership

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Madesh Muniswamy, MS, PhD 
Director
Long Endowed Professor, Department of Medicine
Long School of Medicine

Dr. Muniswamy's PubMed Research

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David Gius, MD, PhD
Co-Director
Professor, Department of Radiation Oncology
Long School of Medicine

Dr. Gius' PubMed Research

Board Members – External

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David Chan, MD, PhD
Professor of Biology, Division of Biology and Biological Engineering
Caltech

Dr. Chan's PubMed Research

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J. Kevin Foskett, PhD
Chair, Department of Physiology
University of Pennsylvania

Dr. Foskett's PubMed Research

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David J. Pagliarini, PhD
Hugo F. & Ina C. Urbauer Professor and BJC Investigator
Departments of Cell Biology and Physiology, Biochemistry and Molecular Biophysics, and Genetics
Washington University School of Medicine in St. Louis

Dr. Pagliarini's PubMed Research

Rexford S., Ahima, MD, PhD

Rexford S. Ahima, MD, PhD
Director, Division of Endocrinology, Diabetes & Metabolism
Professor of Medicine, Public Health, Nursing
Bloomberg Distinguished Professor of Diabetes
Johns Hopkins University

Dr. Ahima's PubMed Research

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